Life Nearly 107,000 drug overdoses, COVID deaths, push US life expectancy to lowest in 25 years December 22, 2022 Natalie Neysa Alund, USA TODAY Comments Off on Nearly 107,000 drug overdoses, COVID deaths, push US life expectancy to lowest in 25 years According to final figures reported by the CDC, 106,699 people died as a result of an overdose, up from 92,000 people who died in 2020.